Vasoactive Med Dosing Rates

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STILL JUST NOTES, UNDER CONSTRUCTION

Agent Indication Dose Approx for 70 kg person
Amiodarone
Diltiazem
Dobutamine To increase CO, SV in cardiogenic shock 2.5-20 mcg/kg/min 150 mcg / min to 1.4 mg/min
Dopamine
Epi
Esmolol
Labetolol
Lidocaine
Milrinone
Nicardipine
Nitroprusside
Norepi
Phenylephrine
Procainamide
Vasopressin

Push-Dose Epi
- 1 mg into 1L NS
(or: waste 9 cc from cardiac amp, refill with saline)
- Now have 10 mcg/mL
- Give 0.5-2 mL, or 5-20 mcg, PRN

Push-dose Phenylephrine
- Draw 1 mL (comes in 10 mg/mL)
- Put into 100 mL NS
- Now have 100 mcg/mL
- 0.5-2 mL, or 50-200 mcg, PRN

Acute CHF / Cardiogenic Shock
Nitroglycerine
SL 400 mcg Q3-5 mins
Gtt 50-100 mcg/min, you can rapidly titrate to 200-400 mcg/min
(Standard nitro concentration is 200 mcg/ml. So 30 mL/hr = 100 mcg/min, 60 mL/hr = 200 mcg/min)

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